Kainic acid (487-79-6) is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. CNS stimulant and neurotoxin. Kainic acid is a classic neuroexcitatory agent for induction of seizures in laboratory animals (typical dose 10-30 mg/kg). 酪氨酸(487-79-6)是一种构象限制性谷氨酸类似物,在酪氨酸受体上起选择性激动剂的作用。 中枢神经刺激和神经毒素。 钾酸是一种经典的神经兴奋剂,可诱导实验室动物癫痫发作(典型剂量为10-30毫克/公斤) .
References/Citations:
1) Watkins et al. (1981), Excitatory amino acid transmitters; Ann. Rev. Pharmacol. Toxicol., 21 165
CAS:
487-79-6
Catalog Number:
10-2453
Activity:
Kainate receptor agonist; neurotoxin
Chemical Name:
(2S,3S,4S)-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid, hydrate
Molecular Weight:
213.24
Solubility:
Soluble in Water (up to 10 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
RT
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
Shipping Code:
RT