Triacetyl resveratrol (CAS 42206-94-0) is a resveratrol prodrug. One method for increasing the half-life of resveratrol in vivo is acetylation of the phenolic OH groups. Deacetylation takes place in vivo or in intact cells via the action of intracellular esterases releasing active resveratrol. 三乙酰白藜芦醇(CAS 42206-94-0)是一种白藜芦醇前药。 提高白藜芦醇在体内半衰期的一种方法是酚羟基乙酰化。 去乙酰化发生在体内或完整细胞中,通过细胞内酯酶释放活性白藜芦醇的作用。
References/Citations:
1) Hsieh et al. (2011), Control of prostate cell growth, DNA damage and repair and gene expression by resveratrol analogues, in vitro; Carcinogenesis, 32 93 2) Hsieh et al. (2011), Regulation of p53 and cell proliferation by resveratrol and it’s derivatives in breast cancer cells: an in silico and biochemical approach to targeting integrin αvβ3; Int. J. Cancer, 129 2732
CAS:
42206-94-0
Catalog Number:
10-2437
Activity:
SIRT activator, prodrug
Chemical Name:
5-[(1E)-2-[4-(Acetyloxy)phenyl]ethenyl]-1,3-benzenediol-1,3-diacetate
Alternate Names:
3,5,4’-Tri-O-acetylresveratrol
Molecular Weight:
364.43
Molecular Formula:
C20H28O6 Solubility:
Soluble in DMSO (up to 25 mg/ml) or in ethanol (up to 8 mg/ml).
Physical Properties:
White solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
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