BRD 7116 (329059-55-4) inhibits leukemia stem cell (LSC) activity (EC50 = 200 nM). Displays a >100-fold selectivity for LSCs over normal hematopoietic stem cells.1 BRD 7116(329059-55-4)抑制白血病干细胞(LSC)活性(EC50 = 200 nM)。 对LSCs的>选择性是正常造血干细胞的100倍 。
References/Citations:
1) Hartwell et al. (2013), Niche-based screening identifies small-molecule inhibitors of leukemia stem cells; Nat. Chem. Biol., 9 840
CAS:
329059-55-4
Catalog Number:
10-1616
Activity:
Leukemia cancer stem cell inhibitor
Chemical Name:
N,N’-(Sulfonyldi-1,4-phenylene)bis[2,2,3,3-tetramethylcyclopropanecarboxamide]
Molecular Weight:
496.66
Molecular Formula:
C28H36N2O4S
Solubility:
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 15 mg/ml)
Physical Properties:
Off-white solid
Purity:
98% by TLC
NMR (Conforms)
Storage Temperature:
-20°C
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Shipping Code:
RT
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