PDX研究

1.E, Amant F. Development of Patient-Derived Tumor Xenograft Models. Methods Mol Biol. 2019;1862:217-25. 

2.Wang Z, Fu S, Zhao J, Zhao W, Shen Z, Wang D, et al. Transbronchoscopic patient biopsy-derived xenografts as a preclinical model to explore chemorefractory-associated pathways and biomarkers for small-cell lung cancer. Cancer Lett. 2019;440-441:180-8.

3.Williams JA. Using PDX for Preclinical Cancer Drug Discovery: The Evolving Field. J Clin Med. 2018;7(3).

4.Wang, X., et al. "EGFR gene status predicts response and survival benefit in a preclinical gastric cancer trial treating patient?derived xenografts with cetuximab. " Oncology Reports 38.4(2017).

5.Verma B, Ritchie M, Mancini M. Development and Applications of Patient-Derived Xenograft Models in Humanized Mice for Oncology and Immune-Oncology Drug Discovery. Curr Protoc Pharmacol. 2017;78:14.41.1-14.41.12.

6.Izumchenko E, Paz K, Ciznadija D, Sloma I, Katz A, Vasquez-Dunddel D, et al. Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors. Ann Oncol. 2017;28(10):2595-605. 

7.Gheibi P, Zeng S, Son KJ, Vu T, Ma AH, Dall'Era MA, et al. Microchamber Cultures of Bladder Cancer: A Platform for Characterizing Drug Responsiveness and Resistance in PDX and Primary Cancer Cells. Sci Rep. 2017;7(1):12277.

8.Lin D, Wyatt A W, Xue H, et al. High fidelity patient-derived xenografts for accelerating prostate cancer discovery and drug development[J]. Cancer Research, 2014, 74(4):1272.

9.Kopetz S , Lemos R , Powis G . The Promise of Patient-Derived Xenografts: The Best Laid Plans of Mice and Men[J]. Clinical Cancer Research, 2012, 18(19):5160-5162.

10.Bertotti A, Migliardi G, Galimi F, Sassi F, Torti D, Isella C, et al. A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer. Cancer Discov. 2011;1(6):508-23.

11.Marangoni E, Vincent-Salomon A, Auger N, et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin Cancer Res 2007; 13:3989-98.