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Synapsin-1-(D12G5)-XP®-Rabbit-mAb

  • 价  格: 询价
  • 品  牌: CST
  • 级  别: 详见MSDS文件
  • 保  质  期: 详见说明书
  • 适应物种: H,M,R
  • 试用规格: Microsize T包装(20ul)
  • 应用范围: W, IP, IHC-P, IF-F
  • 保存条件: -20°c
  • 抗体英文名: Synapsin-1 (D12G5) XP Rabbit mAb__®
  • 是否单克隆: false
  • 产  地: USA
  • 供  应  商: CST
  • 抗  原: synthetic peptide corresponding to residues surrounding Gln483 of human synapsin-1 protein
  • 货  号: 5297
在线询问 已有 7 人申请试用
美国CST中国公司(丁香通商铺)
商家诚信度:
成立时间:2008
入驻丁香通年限:6年
商家等级:金牌客户
产品信息完整度:46.0%
联系人:陈小姐

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电话:021-58356288

邮件:info@cst-c.com.cn

传真:021-58356116

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* 试用品 Synapsin-1 (D12G5) XP® Rabbit mAb (7 人申请)
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试用说明

试用申请时间: 2019年06月24日— 2019年07月26日 1. 运费:顺丰到付(约50-100元不等)
2. 发货时间:7月29~8月2日审核,8月12~16日发货,电话确认申请成功后,请耐心等待2-3周时间收货。
3. 申请要求:务必于3-6个月提交试用报告。
4. 限制条件:仅适合终端客户,一个PI课题组仅限申领一支。
5.备注:请认真填申请理由。

产品详情

规格: 产品价格: 询价

pathway more info application references datasheet PDF MSDS PDF protocols

 

Applications Key:  W=Western Blotting  IP=Immunoprecipitation  IHC-P=Immunohistochemistry (Paraffin)  IF-F=Immunofluorescence (Frozen)
Reactivity Key:  H=Human  M=Mouse  R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

 

Applications Reactivity Sensitivity MW (kDa) Isotype
W IP IHC-P IF-F H M R Endogenous 77 Rabbit IgG
Protocols
Specificity / Sensitivity

Synapsin-1 (D12G5) XP® Rabbit mAb detects endogenous levels of total synapsin protein. The antigen is 100% conserved between human synapsin-1a and synapsin-1b.

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln483 of human synapsin-1 protein.

Western Blotting

Western Blotting

Western blot analysis of extracts from CAD cells and neonatal mouse brain using Synapsin-1 (D12G5) XP® Rabbit mAb.

IHC-P (paraffin)

IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded human cerebellum using Synapsin-1 (D12G5) XP® Rabbit mAb.

IHC-P (paraffin)

IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded mouse cortex using Synapsin-1 (D12G5) XP® Rabbit mAb.

 

IHC-P (paraffin)

IHC-P (paraffin)

Immunohistochemical analysis of paraffin-embedded rat retina using Synapsin-1 (D12G5) XP® Rabbit mAb.

IF-F

IF-F

Confocal immunofluorescent analysis of mouse brain using Synapsin-1 (D12G5) XP® Rabbit mAb (green) and β3-Tubulin (TU-20) Mouse mAb #4466 (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye).

Background

Synapsins, a group of at least five related members (synapsins Ia, Ib, IIa, IIb, and IIIa), are abundant brain proteins essential for regulating neurotransmitter release (1,2). All synapsins contain a short amino-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I (1). Phosphorylation of the synapsin amino-terminal domain at Ser9 inhibits its binding to phospholipids and dissociates synapsins from synaptic vesicles (2).

 

  1. Greengard, P. (1987) Mol Neurobiol 1, 81-119.
  2. Hosaka, M. et al. (1999) Neuron 24, 377-87.
Application References

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Companion Products

For Research Use Only. Not For Use In Diagnostic Procedures.

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