活性:Measured by its binding ability in a functional ELISA. Immobilized Human BAFF, Fc Tag (Catalog # BAF-H4268) at 5μg/mL (100 μL/well) can bind Biotinylated Human BCMA, Fc Tag (Catalog # BC7-H82F0) with a linear range of 0.12-1.95 ng/mL.
产品背景:Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
产品描述:This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 33.8 kDa. As a result of glycosylation, The protein migrates as 40-45 kDa under reducing (R) condition and 70-85 kDa under non-reducing (NR) condition on SDS-PAGE gel.