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鼠NBS1 单克隆抗体
- 参考价格： 询价
- 品 牌： novus
- 货 号： NB100-221APC
- 靶 点： NBS1 查看全部NBS1 抗体
- 适应物种： 人,小鼠,大鼠
- 应用范围： 免疫印迹,免疫细胞化学/免疫荧光,免疫细胞化学,免疫沉淀
- 克 隆 性： Monoclonal
- 宿 主： Mouse
产品概览
| 免疫原： | The complete coding region of the human p95/NBS1 expressed in E. coli. |
| 产品保证说明： | All of our products are backed by our 100% guarantee to work for stated and predicted species and applications. |
| 产品别名： | p95 protein of the MRE11/RAD50 complexNijmegen breakage syndrome 1 (nibrin)ATVMGC87362AT-V2FLJ10155AT-V1NBS1P95NBSNijmegen breakage syndrome protein 1Cell cycle regulatory protein p95nibrin |
| 克隆： | 1D7 |
产品特性
| 纯度： | Protein G purified |
靶点信息
| uniprot： |
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| 基因： | NBN |
| 基因标志： | NBN |
| 基因相关产品： | MRE11A,RAD50,ATM,CHEK2,H2AFX,TP53,BRCA1,ATR,MMAB,ANTXR1,CHEK1,TP53BP1,RAD51,MDC1,PRKDC,BRCA2,RBBP8,CFTR,CDKN1A,RPA |
| 胞内定位： | Nuclear |
| entrez： |
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| uniprot： |
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应用与保存
| 免疫原： | The complete coding region of the human p95/NBS1 expressed in E. coli. |
| 防腐剂： | No Preservative |
| 应用说明： | This product is for research purposes only. For immunoblotting use purified antibody at 1-2 ug/ml. |
| 稀释浓度： |
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其他
| 保存条件： | Store at 4C in the dark. |
| 标记物： | Allophycocyanin (A=650, E=660) |
| 备注： | Optimal dilution of this antibody should be experimentally determined. |
| 浓度： | Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services. |
| 温馨提示： | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies areguaranteedfor 1 year from date of receipt. |
| 特异性： | Nijmegen breakage syndrome (NBS, nibrin) is an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The 1D7 recognizes the 95kDa NBS protein which contains a fork FHA head-associated domain that is adjacent to BRCT, a breast cancer C terminal domain, that has been implicated in protein-protein interactions. NBS is member of the Mre11/Rad50, p400 double-strand break repair complex involved in double-strand break repair and cell-cycle checkpoint functions. |
| 缓冲液： | PBS [pH7.4] |
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