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鼠抗人Lambda light chain 单克隆抗体
- 参考价格： 询价
- 品 牌： novus
- 货 号： NB110-7087
- 靶 点： Lambda light chain 查看全部Lambda light chain 抗体
- 适应物种： 人
- 应用范围： 酶联免疫吸附,免疫细胞化学,免疫组化—冷冻切片,免疫组化—石蜡切片
- 克 隆 性： Monoclonal
- 宿 主： Mouse
产品概览
| 背景： | All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins). |
| 免疫原： | Mixture of light chains of human immunoglobulin. |
| 产品保证说明： | All of our products are backed by our 100% guarantee to work for stated and predicted species and applications. |
| 产品别名： | IGLCimmunoglobulin lambda constant group |
| 克隆： | 2G9 |
产品特性
| 纯度： | Protein A purified |
靶点信息
| 基因： | IGLC@ |
| 基因标志： | IGLC@ |
| 基因相关产品： | BCR,IGL@,IGLC2,MB,TCIRG1,CRAT,PDGFB,GLYAT,IGKC,CAT,YWHAH,RFC2,PRM1,RFC1,SGCA,CD37,NK,RPLP1,ABL1,RAB36 |
| 胞内定位： | Cytoplasmic |
| entrez： |
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应用与保存
| 免疫原： | Mixture of light chains of human immunoglobulin. |
| 防腐剂： | 0.1% Sodium Azide |
| 应用说明： | ELISA, immunohistochemistry frozen and paraffin Optimal dilutions and concentrations should be determined by the end user. |
| 稀释浓度： |
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其他
| 保存条件： | Store at 4C. Do not freeze. |
| 浓度： | Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services. |
| 温馨提示： | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies areguaranteedfor 1 year from date of receipt. |
| 特异性： | Specific for independent constantly expressed epitope of lambda chain. Reacts with free and heavy chain-associated lambda chains. |
| 缓冲液： | PBS. pH 7.4 |
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