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鼠抗人Lamin A + C 单克隆抗体
- 参考价格： 询价
- 品 牌： novus
- 货 号： NBP1-78443
- 靶 点： Lamin A + C 查看全部Lamin A + C 抗体
- 适应物种： 人
- 应用范围： 免疫印迹,免疫细胞化学/免疫荧光,免疫沉淀
- 克 隆 性： Monoclonal
- 宿 主： Mouse
产品概览
| 背景： | Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin A and C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acids internal deletion within the carboxyl-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of LMNA gene |
| 免疫原： | Peptide from human Progerin |
| 产品保证说明： | All of our products are backed by our 100% guarantee to work for stated and predicted species and applications. |
| 产品别名： | renal carcinoma antigen NY-REN-32CDDCprelamin-A/CCDCD1lamin-A/CPRO1,70 kDa laminprogeria 1 (Hutchinson-Gilford type)limb girdle muscular dystrophy 1B (autosomal dominant)dilated 1A (autosomal dominant)LGMD1BLMNL1FPLDLMNCEMD2LFPCMD1ALDP1lamin A/C-like 1LMN1IDCHGPSFPLCMT2B1lamin A/C |
| 克隆： | 13A4D4 |
产品特性
| 纯度： | Protein G purified |
靶点信息
| uniprot： |
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| 基因： | LMNA |
| 基因标志： | LMNA |
| 基因相关产品： | LAMIN A,EMD,INS,PPARG,ZMPSTE24,INTERMEDIATE FILAMENT,C4A,PGR,LAMIN C,ERBB2,TP53,LEP,PRH2,LMNB1,TMEM37,EEF1A2,CCL27,DES,ESR1,TNF |
| uniprot： |
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应用与保存
| 免疫原： | Peptide from human Progerin |
| 防腐剂： | 0.1% Sodium Azide, 0.01% Thimerosal |
| 稀释浓度： |
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其他
| 保存条件： | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| 标记： | Nuclear Envelope Marker |
| 浓度： | 1 mg/ml |
| 温馨提示： | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies areguaranteedfor 1 year from date of receipt. |
| 缓冲液： | PBS |
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