抗人tgf beta1单克隆抗体
- 参考价格: ¥3025.0
- 品 牌: abgent
- 货 号: AO1065a
- 适应物种: 人
- 应用范围: 免疫印迹
- 克 隆 性: 单克隆
- 亚 型: Mouse IgG2a
- 主要序列号: P01137
- 详细信息
- 图片
详细信息
产品概览
背景: | TGF beta(transforming growth factor beta), with 390-amino acid protein (about 43 kDa), is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3,are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression.TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage.REFERENCES1. Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 272. Shizuya Saika. Lab Invest. 2006 Feb;86(2):106-15 |
其他名字: | CED; DPD1; TGFB; TGFbeta; TGFB1 |
克隆名: | 4F9C10,1B11B7 |
靶点信息
基因id: | 7040 |
蛋白名: | TGFB1 |
胞内定位: | Secreted, extracellular space, extracellular matrix |
同义词: | TGFB |
应用与保存
稀释浓度: | WB~~1:500~2000. |
注意事项: | TGF beta1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
参考文献: | 1. Delphine Boche, Colm Cunningham, Fabian Docagne. Neurobiol Dis. 2006 Feb 272. Shizuya Saika. Lab Invest. 2006 Feb;86(2):106-15 |
保存条件: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
标记物: | Purified recombinant fragment of TGFbeta1 expressed in E. Coli. |
其他序列号: | NP_000651.3 |
分子量: | 44341 Da |
功能: | Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. |
规格: | 0.1ml | 价格: | ¥3025.00 |
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