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抗人tspo/pbr 抗体

  • 参考价格: ¥3300.0
  • 品  牌:  abgent
  • 货  号:  AF2121a
  • 适应物种: 
  • 亚  型:  IgG
  • 其他序列号:  NP_000705
  • 浓  度:  100ug/200ul
  • 标 记 物:  0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
  • 详细信息
  • 图片

详细信息

产品概览

背景: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.REFERENCESOral cancer, cigarette smoke and mitochondrial 18kDa translocator protein (TSPO) - In vitro, in vivo, salivary analysis. Nagler R, et al. Biochim Biophys Acta, 2010 May. PMID 20085808.The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals. Costa B, et al. Endocrinology, 2009 Dec. PMID 19846611.Translocator protein blockade reduces prostate tumor growth. Fafalios A, et al. Clin Cancer Res, 2009 Oct 1. PMID 19789311.Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression. Costa B, et al. Psychiatr Genet, 2009 Apr. PMID 19668118.
其他名字: TSPO; PBR; translocator protein (18kDa) ; BZRP; DBI; IBP; MBR; PKBS; PTBR; mDRC; pk18 ; OTTHUMP00000028891; benzodiazapine receptor (peripheral); benzodiazepine peripheral binding site; mitochondrial benzodiazepine receptor; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor

应用与保存

注意事项: TSPO / PBR (isoform) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

其他

参考文献: Oral cancer, cigarette smoke and mitochondrial 18kDa translocator protein (TSPO) - In vitro, in vivo, salivary analysis. Nagler R, et al. Biochim Biophys Acta, 2010 May. PMID 20085808.The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals. Costa B, et al. Endocrinology, 2009 Dec. PMID 19846611.Translocator protein blockade reduces prostate tumor growth. Fafalios A, et al. Clin Cancer Res, 2009 Oct 1. PMID 19789311.Genetic susceptibility to distinct bladder cancer subphenotypes. Guey LT, et al. Eur Urol, 2010 Feb. PMID 19692168.Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression. Costa B, et al. Psychiatr Genet, 2009 Apr. PMID 19668118.
保存条件: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
规格: 0.1mg 价格: ¥3300.00

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