| 理论分子量： | 55 |
| 基因别名： | CPC8,MP-12/MP-20 |
| 基因名： | CYP2C8 |
| 基因描述： | cytochrome P450, family 2, subfamily C, polypeptide 8 |
| 基因概览： | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq |
| 蛋白序列号： | NP_000761.3;NP_001185782.1;NP_001185783.1 |
| 别名： | OTTHUMP00000020134,P450 form 1,cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8,flavoprotein-linked monooxygenase,microsomal monooxygenase,s-mephenytoin 4-hydroxylase,xenobiotic monooxygenase |
