Enough antisera to induce disease in at least 25 rats. Qualility antisera used in academics and the pharmaceutical industry! Use in mice not validated by Probetex, but successfully used by multiple investigators
Probetex offers a unique source of Nephrotoxic Antisera (anti-GBM, anti-Fx1A, and anti-Thy-1) to induce classical immune models of renal disease. Immune-mediated crescentic glomerulonephritis, Passive membranous (Heymann Nephritis, Mesangioproliferative GN
for the Induction of Immune-Mediated Glomerulonephritis.
Mesangial Proliferation
Inflammatory Cell Vasculitis
Glomerulosclerosis
Renal Fibrosis Note: this product replaces a previous PTX-001S Sheep anti whole rat glomeruli. Both products target rat GBM and produce the same disease model. Not validated or recommended for mice.
咨询热线:400-004-3669
Probetex, Inc. is a life science and contract research organization (CRO) founded in 1997, The company lists six specialization areas including 1) A cell bank of adult and embryonic kidney cell lines; 2) Production and sale of sheep nephrotoxic antibodies to induce anti-glomerular basement membrane (anti-GBM) glomerulonephritis, membranous (anti-Fx1A) nephropathy, and mesangioproliferative (anti-Thy1) glomerulonephritis. 3) Tissue products from renal disease models; 4) Histopathology services providing routine histology, immunohistochemistry, electron microscopy and image analysis; 5) Custom contract research specializing in the above models as well as over 20 other models of acute and chronic experimental kidney disease, cardiovascular liver and lung disease; and 6) other specialty areas such as regenerative medicine and a new initiative to raise funds for the development of new models of anti-neutrophil cytoplasmic antibody(ANCA) vasculitis. Probetex also assists in the assessment and development of rare disease models.