Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Cell membrane Endoplasmic reticulum membrane Endosome membrane Golgi apparatus Lysosome membrane Single-pass type I membrane protein Trans-Golgi network membrane
免疫原
Recombinant protein of human HLA-DQA1
亚型
IgG
纯化方法
Affinity purification
背景资料
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
克隆类型
Polyclonal Antibody
交叉反应
Human Mouse
应用
WB IHC
规格
50ul 100ul
备注:
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示:
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图
Western blot analysis with HLA-DQA1 antibody diluted at 1:1000;Lane:SW620,HT-29,Lovo,Mouse brain,Mouse stomach
Immunohistochemistry of paraffin-embedded Human prostate with HLA-DQA1 antibody diluted at 1:100