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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide
- 形态:
Liquid
- 保存条件:
Store lyophilized/reconstituted at -20°C; once rec
- 克隆性:
Polyclonal
- 适应物种:
Human
- 抗原来源:
Q71DI3
- 级别:
分子生物学级
- 供应商:
Agrisera
- 宿主:
Rabbit
- 应用范围:
2-5 µg/million cells (ChIP), 1 :40 (Dot), 1 : 100 (IF), 1 : 500-1 : 1000 (WB)
- 靶点:
Common histone modifications include methylation of lysine and arginine, acetylation of lysine, phosphorylation of threonine and serine, and sumoylation, biotinylation, and ubiquitylation of lysine. Trimethylation of lysine 56 on H3 is a novel modificatio
- 抗体名:
H3K56me3 | Histone H3 (trimethylated Lys56)
- 规格:
50 µg
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文献和实验Angew. Chem:刘涛 / 罗小舟 / 刘小云团队在组蛋白表观遗传学研究中取得进展
氨基酸以外的吡咯赖氨酸通过遗传编码的方式编码到蛋白中。因此,吡咯赖氨酸成为了古生菌中一种独特存在的共翻译修饰(Co-Translational Modification,CTM)方式。 受到这一修饰方式的启发,文章以酿酒酵母为模式生物,借助基因密码子扩展(Genetic Code Expansion,GCE)技术创造出一种含有 CTM 核小体的酵母菌株,研究人员发现与组蛋白 H3K56 位点巴豆酰化共修饰相比,该菌株中组蛋白 H3K56 位点的乙酰化共修饰能够为酿酒酵母 DNA 损伤修复提供
Identifying Differential Histone Modification Sites from ChIPseq Data
a hidden Markov model (HMM) to infer the states of histone modification changes at each genomic location. We evaluated the performance of ChIPDiff by comparing the H3K27me3 modification sites between mouse embryonic stem cell (ESC) and neural progenitor
upon the dual pulldown to incorporate a third pulldown which is an iteration of the ChIP and is a pulldown for H3K27me3+ (Figure 1b). The third assay described here is the biotin-RNA pulldown of a low-copy RNA that spans the siRNA targeted promoter region
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