T-SkinTM is an in vitro reconstructed skin which consists of a dermal equivalent with human fibroblasts overlaid by a stratified, well differentiated epidermis derived from normal human keratinocytes. The model is cultured on an inert polycarbonate filter. This model exists at different stages of maturity. The model is widely used in efficacy study and safety test in vitro of Photoprotection, Anti aging, Genotoxicity, Permeability, OMICS, Bacterial adhesion, DNA damage, etc…