Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
适应物种:
Human
库存:
100
宿主:
Mouse
应用范围:
WB, E
靶点:
This THBS1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 763-789 amino acids from the Central region of human THBS1.
抗体名:
TSP, TSP1
规格:
100 μl
分子量:
129383 Da
细胞定位:
Antigen Cellular Localization:Endoplasmic reticulum. Sarcoplasmic reticulum
形式:
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
参考文献:
Zhou, L., et al. Cancer Res. 70(20):8199-8210(2010)Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Nucera, C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10649-10654(2010)Gustavsson, H., et al. BMC Cancer 10, 288 (2010) :
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality THBS1 antibody (Center).
功能:
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity).
总结:
The protein encoded by this gene is a subunit of adisulfide-linked homotrimeric protein. This protein is an adhesiveglycoprotein that mediates cell-to-cell and cell-to-matrixinteractions. This protein can bind to fibrinogen, fibronectin,laminin, type V collagen and integrins alpha-V/beta-1. This proteinhas been shown to play roles in platelet aggregation, angiogenesis,and tumorigenesis.
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