TMT (Tandem Mass Tag) 技术和 iTRAQ (Isobaric tag for relative and absolute quantitation)技术是一种间接定量技术,不同同位素标签对各个样品的多肽氨基基团进行特异性标记后,等量混合经串联质谱分析,得到的肽段谱图中各个样品的同位素标签作为差异基准进行定量计算。
In-depth proteomic profiling of left ventricular tissues in human end-stage dilated cardiomyopathy. Oncotarget 2017 IF=5 ITRAQ
pGlyco 2.0 enables precision N-glycoproteomics with comprehensive quality control and one-step mass spectrometry for intact glycopeptide identification. Nature Comm 2017 IF=13 GLYCO
Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2. Nature Comm 2017 IF=13 PHOSPHO
VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2. Nature Comm 2017 IF=13 SILAC
Plasma Membrane CRPK1-Mediated Phosphorylation of 14-3-3 Proteins Induces Their Nuclear Import to Fine-Tune CBF Signaling during Cold Response. Molecular Cell 2017 IF=14 LFQ
Interleukin-6 Induced “Acute” Phenotypic Microenvironment Promotes Th1 Anti-Tumor Immunity in Cryo-Thermal Therapy Revealed By Shotgun and Parallel Reaction Monitoring Proteomics Theranostics 2016 IF=8 ITRAQ+PRM
Label-Free Quantitative Phosphoproteomic Analysis Reveals Differentially Regulated Proteins and Pathway in PRRSV-Infected Pulmonary Alveolar Macrophages. Journal of Proteome Res 2014 IF=5 LFQ
Detergent-Insoluble Proteome Analysis Revealed Aberrantly Aggregated Proteins in Human Preeclampsia Placentas Journal of Proteome Res 2017 IF=5 DIA
High throughput and accurate serum proteome profiling by integrated sample preparation technology and single-run data independent mass spectrometry analysis
Journal of Proteome Res 2017 IF=5 DIA
Propafenone suppresses esophageal cancer proliferation through inducing mitochondrial dysfunction Am J Cancer Res 2017 IF=4 DIA