产品货号:jlcR40122 英文名称 :Apg12 中文名称 :自噬相关蛋白12抗体 别 名 :APG12-like; APG12L; ATG12; ATG12 autophagy related 12 homolog; Autophagy 12; Autophagy-related protein 12; HAPG12; Ubiquitin-like protein ATG12; ATG12_HUMAN. 研究领域 :肿瘤 免疫学 细胞凋亡 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, 产品应用 :WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :15/21kDa 细胞定位 :细胞浆 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human Apg12:101-187/187 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998[PubMed 9852036]).[supplied by OMIM].
Function: Ubiquitin-like protein required for autophagy. Conjugated to ATG3 and ATG5.
Subcellular Location: Cytoplasm.
Tissue Specificity: Ubiquitous.
Similarity: Belongs to the ATG12 family.
SWISS: O94817
Gene ID: 9140
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.