产品名称：人肝细胞
人肝细胞 (Cat. #5200)
英文名称：Human Hepatocytes
货号：5200
品牌：ScienCell
产地：美国
规格：1x10^6，1ml
价格：$671
产品说明
肝脏是许多重要功能的关键器官，包括能量代谢、外源性化学物质生物转化、生理和病理条件下血浆蛋白合成、以及解毒作用。人肝细胞是多功能细胞，包括蛋白质合成、胆固醇合成、储存蛋白质、产生并分泌胆汁以及解毒作用。HH是体外培养用来研究肝功能、新陈代谢和肝病非常好的模型。了解肝脏的分子机制可能有助于阐明治疗肝脏疾病的新疗法。
Sciencell研究实验室的脐静脉内皮细胞是从人肝脏分离得到的，原代冻存，冰冻运输。每管细胞密度超过5×10^6/ml。细胞特性经白蛋白、cytokeratin-18 and vimentin免疫荧光鉴定。本细胞经检测不含HIV-1、HBV、HCV、支原体、细菌、酵母菌和真菌。HH不能扩大培养或者产期培养，因为它不能增殖。
推荐培养基
肝细胞培养基 (HM, Cat. #5201)
使用说明
人肝细胞仅用于科研。不能用于人或动物和体外诊断应用。
储存
接收到冻存细胞时请立即从干冰转入液氮中保存。
运输
干冰运输。
文献
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6.) Shen Q, Cicinnati VR, Zhang X, Iacob S, Weber F, Sotiropoulos GC, Radtke A, Lu M, Paul A, Gerken G, Beckebaum S. (2010) "Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion." Mol Cancer. 9: 227.
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8.) Yeon JH, Na D, Park JK. (2010) "Hepatotoxicity assay using human hepatocytes trapped in microholes of a microfluidic device." Electrophoresis. 31: 3167-74.
9.) Braconi C, Meng F, Swenson E, Khrapenko L, Huang N, Patel T. (2009) "Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures." Cancer. 115: 3738-48.
10.) Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y. (2009) "Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis." Cancer Res. 69: 7529-37.
11.) Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. (2007) "MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer." Gastroenterology. 133: 647-58.
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