The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
1:500 - 1:2000
IHC
1:50 - 1:200
Western blot analysis of extracts of various cell lines, using MYD88 antibody.
Immunohistochemistry of paraffin-embedded rat lung using MYD88 Antibody.
Immunohistochemistry of paraffin-embedded rat kidney using MYD88 Antibody.
Immunohistochemistry of paraffin-embedded human colon using MYD88 Antibody.
Immunohistochemistry of paraffin-embedded human colon carcinoma using MYD88 Antibody.
Background:
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Storage:
Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.