Plays an important role in endoplasmic reticulum- associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).
产品描述
anti-FAF2 antibody is a Rabbit Polyclonal antibody againstFAF2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human testis using PAab02947(FAF2 antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab02947(FAF2 antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!)