May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA.
产品描述
anti-ABI2 antibody is a Rabbit Polyclonal antibody againstABI2..
建议稀释比例
WB :1:500-1:5000;IHC:1:20-1:200;IF:1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human brain tissue slide using PAab00052( ABI2 Antibody) at dilution of 1:50
Western blot
mouse heart tissue were subjected to SDS PAGE followed by western blot with PAab00052(ABI2 antibody) at dilution of 1:400(本抗体仅供体外科研用途,不可用于临床诊断!)