Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
Western blot analysis of GPX4 expression in (1) HepG2 cell lysate; (2) Mouse testis lysate.
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