Product overview
Description Anti-GFI1B rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GFI1B
Reactivity Human
Content 1.14 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-GFI1B antibody Target information
Symbol GFI1B
Full name growth factor independent 1B transcriptional repressor
Synonyms BDPLT17; ZNF163B
Swissprot Q5VTD9
Target Background
This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants.
Anti-GFI1B antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 50-300