Product overview
Description Anti-GEMIN4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human GEMIN4
Reactivity Human
Content 0.54 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GEMIN4
Full name gem nuclear organelle associated protein 4
Synonyms p97; HC56; HCAP1; HHRF-1
Swissprot P57678
Target Background
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Anti-GEMIN4 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100