Product overview
Description Anti-RAP1A rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Full length fusion protein
Reactivity Human, Mouse, Rat
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol RAP1A
Full name RAP1A, member of RAS oncogene family
Synonyms RAP1; C21KG; G-22K; KREV1; KREV-1; SMGP21
Swissprot P62834
Target Background
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAP