Product overview Description Anti-CCR7 rabbit polyclonal antibody Applications ELISA, WB Immunogen Synthetic peptide of human CCR7 Reactivity Human Content 0.2 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol CCR7 Full name C-C chemokine receptor type 7 Synonyms BLR2, EBI1, CD197, CDw197, CMKBR7 Swissprot P32248
Target Background The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Applications Western blotting Predicted band size:43 kDa Positive control:293T cells Recommended dilution: 200-1000
Gel: 10%SDS-PAGE Lysate: 40 μg Lane: 293T cells Primary antibody: ml260153(CCR7 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1.5 minutes