The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
克隆性:
多克隆
供应商:
安诺伦(北京)生物科技有限公司
应用范围:
FC, FA
规格:
500 μg
研究领域:Adaptive Immunity
来源:Mouse IgG1, kappa
存储溶液:Phosphate-buffered aqueous solution, ph7.2.
参考文献:Hirji, N., Lin, T. J., Bissonnette, E., Belosevic, M., & Befus, A. D. (1998). Mechanisms of macrophage stimulation through CD8: macrophage CD8α and CD8β induce nitric oxide production and associated killing of the parasite Leishmania major. The Journal of Immunology, 160(12), 6004-6011.Hirji, N., Lin, T. J., & Befus, A. D. (1997). A novel CD8 molecule expressed by alveolar and peritoneal macrophages stimulates nitric oxide production. The Journal of Immunology, 158(4), 1833-1840.Torres‐Nagel, N., Kraus, E., Brown, M. H., Tiefenthaler, G., Mitnacht, R., Williams, A. F., & Hünig, T. (1992). Differential thymus dependence of rat CD8 isoform expression. European journal of immunology, 22(11), 2841-2848.
简单描述:The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that macrophages express CD8 alpha and beta chains for signal transduction. CD8 is an antigen co-receptor that interacts with MHC class I molecules on antigen-presenting cells.