pp52 (UL44) is the DNA polymerase processivity subunit of CMV. It is a phosphorylated protein, with a high presence in the virus and DNA binding capacity. pp52 corresponds to an immediate early antigen. It is one of the serological targets for detection of CMV-specific IgM.
Serodiagnosis of latent infection or active infection in immunocompetent individuals; presence of CMV in associated diseases and transplantation, especially in immunocompromised individuals; diagnosis of congenital infection in newborns and intrauterine primary infection in pregnant women.