DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体

DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体

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  • ¥780 - 2200
  • LMAI Bio
  • LM-6003R
  • 进口/国产
  • 2025年11月18日
  • WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)
  • Rabbit
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 目录编号

      LM-6003R

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      DAL1/EPB41L3

    • 抗体名

      细胞骨架4.1蛋白家族DAL1抗体

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,

    • 免疫原

      KLH conjugated synthetic peptide derived from human DAL1/EPB41L3:131-230/1087

    • 亚型

      IgG

    • 形态

      Lyophilized or Liquid

    • 应用范围

      WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复)

    • 浓度

      1mg/ml

    • 保存条件

      Store at -20 °C

    • 规格

      50ul  100ul  200ul

    DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体
    英文名称 DAL1/EPB41L3
    中文名称 细胞骨架4.1蛋白家族DAL1抗体
    别    名 Differentially expressed in adenocarcinoma of the lung protein 1; 4.1B; Band 4.1 like protein 3; DAL 1; DAL1; EPB41L3; Erythrocyte membrane protein band 4.1 like 3; HGNC:3380; KIAA0987; E41L3_HUMAN.  
    规格价格 50ul/780元 购买    100ul/1380元 购买    200ul/2200元 购买    大包装/询价
    说 明 书 50ul  100ul  200ul
    研究领域 肿瘤  细胞生物  免疫学  神经生物学  细胞骨架  细胞膜蛋白  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, 
    产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 120kDa
    细胞定位 细胞浆 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human DAL1/EPB41L3:131-230/1087 
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    PubMed PubMed
    产品介绍 background:
    EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.

    Function:
    Critical growth regulator in the pathogenesis of meningiomas. 

    Subunit:
    Interacts with CADM1. 

    Subcellular Location:
    Cytoplasm, cytoskeleton

    Tissue Specificity:
    Expressed at high levels in brain, with lower levels in kidney, intestine, and testis.

    Similarity:
    ontains 1 FERM domain.

    SWISS:
    Q9Y2J2

    Gene ID:
    23136

    Database links:

    Entrez Gene: 23136 Human

    Entrez Gene: 13823 Mouse

    Entrez Gene: 116724 Rat

    Omim: 605331 Human

    SwissProt: Q9Y2J2 Human

    SwissProt: Q9WV92 Mouse

    Unigene: 213394 Human

    Unigene: 131135 Mouse



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 
     
    产品图片 DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体
    Sample: 
    Brain (Mouse) Lysate at 40 ug
    Brain (Rat) Lysate at 40 ug
    U-87MG (Human) CellLysate at 30 ug
    HepG2 (Human) CellLysate at 30 ug
    Primary: Anti-DAL1/EPB41L3 (bs-6003R) at 1/500 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 120 kD
    Observed band size: 130-140 kD

    DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体
    Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAL1(EPB41L3)) Polyclonal Antibody, Unconjugated (bs-6003R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
    DAL1/EPB41L3细胞骨架4.1蛋白家族DAL1抗体
    Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAL1(EPB41L3)) Polyclonal Antibody, Unconjugated (bs-6003R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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