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    Toll样受体9抗体

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    Toll样受体9抗体

    丁香通用户服务中心 查看详情

      • 货号:

        GD-011

      • 保存条件:

        连续使用时4°C存储,保质期六个月;长期存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

      • 浓度:

        1mg/1ml

      • 应用范围:

        WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

      • 免疫原:

        KLH conjugated synthetic peptide derived from hu MEK6

      • 适应物种:

        hu, mo, rat

      • 宿主:

        Goat,Rabbit,Mouse

      • 抗体名:

        Toll样受体9抗体

      • 抗体英文名:

        Anti-TLR9/CD289

      • 保质期:

        详见说明书

      • 抗原来源:

        Rabbit

      • 克隆性:

        多克隆

      • 数量:

        1000

      • 供应商:

        上海古朵生物科技有限公司

      • 规格:

        0.1ml/100μg 0.2ml/200μg

      上海古朵生物专业销售Toll样受体9抗体、进口标准品/对照品,中药标准品,色谱标准品,标准品新品,国产/进口Elisa试剂盒,96T/48TElisa试剂盒, 96T/48Telisakit价格,国产/进口血清,生化试剂,标准品|对照品、培养基等科研生化 试剂,品质保证,技术严格,欢迎来电咨询及订购。

      英文名称 :Anti-TLR9/CD289

      中文名称 :Toll样受体9抗体

      英文别 名 :Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B; TLR9_HUMAN.

      浓 度 : 1mg/1ml

      规 格 :0.1ml/100μg 0.2ml/200μg

      使用范围:仅限科研使用,不能应用于临床

      应用:IH(P)免疫组化(石蜡)IC细胞免疫化学;WB免疫印迹;FC流式细胞检测;ELISA

      保存条件:连续使用时4°C存储,保质期六个月;长期存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

      抗体来源 :Rabbit

      克隆类型 :polyclonal

      交叉反应 :Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

      产品类型 :一抗

      研究领域: 免疫学 神经生物学 信号转导 细胞周期蛋白

      蛋白分子量: predicted molecular weight: 113kDa

      性 状 :Lyophilized or Liquid

      免 疫 原 :KLH conjugated synthetic peptide derived from human TLR9

      亚 型 :IgG

      纯化方法 :affinity purified by Protein A

      储 存 液 :0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

      保存条件 :
      Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
      Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

      产品介绍 :
      TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
      Function : Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
      Subunit : Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1 (By similarity). Interacts with BTK.
      Subcellular Location : Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity). Endosome (By similarity). Lysosome (By similarity). Cytoplasmic vesicle, phagosome (By similarity). Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist (By similarity).
      Tissue Specificity : Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c immature dendritic cells. Also detected in lung and liver.
      Similarity : Belongs to the Toll-like receptor family. Contains 26 LRR (leucine-rich) repeats. Contains 1 TIR domain.
      Database links : UniProtKB/Swiss-Prot: Q9NR96.2

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    6 年  VIP 供应商

    上海古朵生物科技有限公司

    • 联系人:

      王经理

    • 所在地区:

      上海市浦东新区川沙经济园区

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