WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
25-28kDa
细胞定位
分泌型蛋白
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human Serum amyloid P component:31-130/223
亚 型
IgG
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
PubMed
PubMed
产品介绍
background: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008].
Subunit: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
Subcellular Location: Secreted.
Tissue Specificity: Found in serum and urine.
DISEASE: Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
SWISS: P02743
Gene ID: 325
Database links:
Entrez Gene: 325 Human
Omim: 104770 Human
SwissProt: P02743 Human
Unigene: 507080 Human
产品图片
Sample: Muscle (Mouse) Lysate at 40 ug Primary: Anti-Serum Amyloid P (bs-3765R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25/28 kD Observed band size: 25 kD
Sample: Hemoprotein (Mouse) Lysate at 40 ug Primary: Anti-Serum Amyloid P (bs-3765R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25/28 kD Observed band size: 25 kD