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PeproTech重组人GM-CSF 5ug

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供应商信息

派普泰克生物科技(苏州)有限公司(PeproTech中国)
商家诚信度:
成立时间:1988
入驻丁香通年限:8年
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产品信息完整度:71%
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产品详情

品牌: PeproTech
货号: 300-03-5
保存条件: -20oC
保质期: 1年以上
数量: 大量
供应商: PeproTech(派普泰克)
CAS号:
规格: 5ug
 

Synonyms :

Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α

Description :

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Catalog #:

300-03

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

The ED 50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

Selected References :

Selected List of References Citing This Product

AA Sequence :

MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE

PubMed Link :

GM-CSF+AND+human

Country of Origin :

USA

 

 

 

Size A 5µg $80   
 
Size B 20µg $195   
 
Size C 1mg $3250   
 

 


 

Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.

 

Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

温馨提示:不可用于临床治疗。

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品牌:novus  应用:流式细胞技术,免疫细胞化学/免疫荧光  价格:询价 
产品名:重组人GM-CSF产品号:LT0094产品信息:GM-CSF在体外可刺激中性粒细胞和巨噬细胞的集落形成,并具有促进早期红巨核细胞、嗜酸性祖细胞增殖和发育的功能。GM-CSF是发现最早的对于DC有作用的细胞因子之一。GM-CSF在DC培养中的功能是促进单核细胞向大巨噬样细胞分化,促进细胞表面MHC Ⅱ类分子的表达,从而增强细胞的抗原递呈功能。此外,GM-CSF还可促进DC的存活。GM-CSF在多种肿瘤模型中表现出激活免疫反应的活性。GM-CSF抗肿瘤活性来源于其激活巨噬细胞和树突状细胞(DCs)的生物学功能。GM-CSF还能促进DC细胞成熟,促进共刺激分子上调和CD1d受体表达,从而参与抗原呈递功能。早期的研究表明CD4+和CD8+ T细胞参与了GM-CSF激活的抗肿瘤免疫。最近的研究表明GM-CSF参与的抗肿瘤活性中,NKT起到重要作用。别名:Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α英文描述:GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kD志道lt-0094-050
产品信息:GM-CSF在体外可刺激中性粒细胞和巨噬细胞的集落形成,并具有促进早期红巨核细胞、嗜酸性祖细胞增殖和发育的功能。GM-CSF是发现最早的对于DC有作用的细胞因子之一。GM-CSF在DC培养中的功能是促进单核细胞向大巨噬样细胞分化,促进细胞表面MHC Ⅱ类分子的表达,从而增强细胞的抗原递呈功能。此外,GM-CSF还可促进DC的存活。GM-CSF在多种肿瘤模型中表现出激活免疫反应的活性。GM-CSF抗肿瘤活性来源于其激活巨噬细胞和树突状细胞(DCs)的生物学功能。GM-CSF还能促进DC细胞成熟,促进共刺激分子上调和CD1d受体表达,从而参与抗原呈递功能。早期的研究表明CD4+和CD8+ T细胞参与了GM-CSF激活的抗肿瘤免疫。最近的研究表明GM-CSF参与的抗肿瘤活性中,NKT起到重要作用。别名:Granulocyte-Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, Pluripoietin-α英文描述:GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consis志道lt-0094-010
Recombinant Human GM-CSF 产品编号: 300-03 别名: Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α 描述: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. 氨基酸序列:MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF 来源: E.coli 纯度: Greater than 98% by SDS-
Recombinant Human GM-CSF 产品编号: 300-03 别名: Granulocyte/Macrophage Colony-Stimulating Factor,CSF-2,MGI-1GM,pluripoietin-α 描述: GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. 氨基酸序列: MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE 来源: E.coli 纯度: Greater than 98%

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