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PeproTech重组人IL-1alpha 2ug

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派普泰克生物科技(苏州)有限公司(PeproTech中国)
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成立时间:1988
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产品详情

品牌: PeproTech
货号: 200-01A-2
供应商: PeproTech(派普泰克)
保存条件: -20oC
保质期: 1年以上
CAS号:
数量: 大量
规格: 2ug
 

Synonyms :

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)

Description :

IL-1α is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.

Catalog #:

200-01A

Source :

E.coli

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

The ED 50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.

Selected References :

Selected List of References Citing This Product

AA Sequence :

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

PubMed Link :

IL-1+AND+alpha

Country of Origin :

USA

 

 

 

Size A 2µg $80   
 
Size B 10µg $195   
 
Size C 1mg $5200   
 

 


 

Special Sizes:
Many products can be ordered in custom sizes. Please click here to contact with your request.

 

Usage:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

温馨提示:不可用于临床治疗。

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产品信息:白细胞介素-1β,简称白介素1β(IL-1β),是一种细胞因子,属于白细胞介素1家族。它是由活化的巨噬细胞所产生的前体经Caspase 1 (CASP1/ICE)酶切生成。IL-1β作为一个重要的炎症应答中间因子,能够参与免疫反应中的多种细胞活动,包括细胞增殖、分化和凋亡。在中枢神经系统中由IL-1β诱导产生的cyclooxygenase-2 (PTGS2/COX2)被证明与炎症疼痛过敏有关。别名:Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)英文描述:IL-1β is a proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells.  Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties.  These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the release of prostaglandin and collagenase from synovial cells.  However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine.  Recombinant Human IL-1志道lt-0111-010
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本公司代理多种品牌耗材, 如需订购请联系24小时为您服务: 公司电话:021-61507986 手    机:15601775891 Q      Q:1597844312 Recombinant Murine IL-1β 产品编号: 211-11B 别名: Catabolin,Lymphocyte-activating factor (LAF),Endogenous Pyrogen (EP),Leukocyte Endogenous Mediator (LEM),Mononuclear Cell Factor (MCF) 描述: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant murine IL-1β is a 17.5 kDa protein contain
本公司代理多种品牌耗材,如需订购请联系24小时为您服务:公司电话:021-61507986手    机:15601775891Q      Q:1597844312 Recombinant Human IL-1β 产品编号: 200-01B 别名: Catabolin,Lymphocyte-activating factor (LAF),Endogenous Pyrogen (EP),Leukocyte Endogenous Mediator (LEM),Mononuclear Cell Factor (MCF) 描述: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues

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