Human PD-L1 ELISA kit [28-8] (ab277712) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human PD-L1 protein in human serum, plasma, cell culture supernatant, urine, and cell extract samples. It uses our proprietary SimpleStep ELISA® technology and our recombinant PD-L1 antibody clone [28-8]. Quantitate Human PD-L1 with 3.75 pg/mL sensitivity.
-Single-wash protocol reduces assay time to 90 minutes or less -High sensitivity, specificity and reproducibility from superior antibodies -Fully validated in biological samples -96-wells plate breakable into 12 x 8 wells strips
A 384-well SimpleStep ELISA® microplate (ab203359) is available to use as an alternative to the 96-well microplate provided with SimpleStep ELISA® kits.
说明
PD-L1 (also known as CD274 or B7-H1) is a membrane bound glycoprotein involved in regulation of the immune system. PD-L1 is expressed on a variety of inflammatory-activated cells as well as some carcinomas and in melanoma. PD-L1 binds to PD-1 and CD80, where it can suppress T cell activation and proliferation as well as induce apoptosis. Levels of PD-L1 are increased in the plasma of cancer patients as well as in cerebrospinal fluid of gliomas. PD-L1 can bind PD-1 in order to regulate T cell apoptosis.
Abcam has not and does not intend to apply for the REACH Authorisation of customers’ uses of products that contain European Authorisation list (Annex XIV) substances. It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.