Background: Apolipoprotein A-I belongs to the apolipoprotein A1/A4/E family. It is the major protein component of high density lipoprotein (HDL) in plasma and has a specific role in lipid metabolism. ApoA1 participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). Defects in ApoA1 are a cause of high density lipoprotein deficiency type 2 (HDLD2), the low HDL levels observed in high density lipoprotein deficiency type 1 (HDLD1) and amyloidosis type 8 (AMYL8).
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti- ApoA1 antibody recognizes ApoA1 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
Western blot:
Western blot analysis of ApoA1 protein. Whole- cell lysates of HEK- 293T cell was blotted with the anti-ApoA1 rabbit polyclonal antibody (Cat. # 21113).