部分优势的产品和技术平台介绍: 各种样品核酸纯化,尤其是困难特殊样品如多糖多酚含量丰富植物、粪便、土壤等的核酸分离。
荧光定量PCR,反转录荧光定量PCR检测。
大规模发酵罐表达医药级设备纯化科研工具酶,包括各种DNA聚合酶、T4 连接酶、各种突变改造 反转录酶、RNA酶抑制剂等。
PCR产物克隆,TA克隆连接。
Western Blot 全套相关试剂和服务。
3,6-Dihydroxyflavone Suppresses Breast Carcinogenesis by Epigenetically Regulating miR-34a and miR-21. Cancer Prev Res 2015, 8(6)
Expressions of miR-181a and miR-20a in RPMI8226 cell line and their potential as biomarkers for multiple myeloma.Tumor Biol 2015, DOI 10.1007/s13277-015-3600-2 , Published online:02 June 2015
3,6-dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Sci Rep. 2016; 6: 28858.Published online 2016 Jun 27. doi: 10.1038/srep28858
Genome-Wide Analysis of microRNA Responses to the Phytohormone Abscisic Acid in populus euphratica. Frotiers in Plant Science 2016, published: 17 August 2016 doi: 10.3389/fpls.2016.01184
Identification of phasiRNAs and their drought-responsiveness in Populus trichocarpa. FEBS letters. 2016, online: 12 September DOI: 10.1002/1873-3468.12419
High-throughput sequencing of pituitary and hypothalamic microRNA transcriptome associated with high rate of egg production BMC Genomics 2017, 18:255
3,6-Dihydroxyflavone regulates microRNA-34a through DNA methylation. BMC Cancer 2017, 17:619
MiR-181b regulates autophagy in a model of Parkinson’s disease by targeting the PTEN/Akt/mTOR signaling pathway. Neuroscience Letters 2018, 675: 83-88
Insights into the MicroRNA-regulated response of bermudagrass to cold and salt stress. Environmental and Experimental Botany 2018, 145: 64-74
MiR-1 inhibits prostate cancer PC3 cells proliferation through the Akt/mTOR signaling pathway by binding to c-Met.Biomedicine & Pharmacotherapy 2019, 109:1406-1410
Expressed microRNA associated with high rate of egg production in chicken ovarian follicles.Animal Genetics 2017, 4(48): 205-216
Vitamin D receptor activation protects against lipopolysaccharide-induced acute kidney injury through suppression of tubular cell apoptosis. American Journal of Physiology-Renal Physiology 2019, https://doi.org/10.1152/ajprenal.00332.2018
MiR-216b inhibits osteosarcoma cell proliferation, migration, and invasion by targeting Forkhead Box M1. Journal of Cellular Biochemistry 2019, 120(4): 5435-5443
MicroRNA-146b Overexpression Promotes Human Bladder Cancer Invasion via enhancing ETS2-mediated mmp2 mRNA Transcription. Molecular Therapy: Nucleic Acid 2019, doi: https://doi.org/10.1016/j.omtn.2019.04.007.
Identification of lncRNA‐155 encoded by MIR155HG as a novel regulator of innate immunity against influenza A virus infection. Cellular microbiology 2019, https://doi.org/10.1111/cmi.13036.