T Helper Cell Differentiation RT² Profiler™ PCR Array profiles the expression of 84 key genes regulating the commitment of precursor T cells to differentiate into specific effector subtypes. The two more well-known and characterized T helper cell subtypes, Th1 and Th2 cells, mediate cellular and humoral immune responses. Many published research studies find that one subtype population and its immune response tends to dominate in immune disorders such as allergy, asthma, autoimmunity, diabetes, hypersensitivity, and rheumatoid arthritis. The genes represented by this array include cytokines, cytokine receptors, transcription factors, and other signaling molecules regulating differentiation into Th1 or Th2 cells as well as specific markers for these subtypes. Profiling your research RNA samples from T cell population sources will help you correlate sub-type specific gene expression with experimentally-induced cellular or humoral immune responses. The results of this array can also help you provide insights into the molecular mechanisms and biological pathways behind T helper cell lineage commitment decisions in your model system. Using real-time PCR, your research study can easily and reliably analyze the expression of a focused panel of genes involved in T helper cell differentiation with this array.