样品要求 血清样品:2-4ml
外泌体样品:1ml
RNA样品:500ng
参考文献 Tkach M, et al. Communication by Extracellular Vesicles: Where We Are and Where We Need to Go. Cell. 2016 Mar 10;164(6):1226-32
Enderle D, Spiel A, Coticchia CM, Berghoff E, Mueller R, Schlumpberger M, et al.Characterization of RNA from Exosomes and Other Extracellular Vesicles Isolated by a Novel Spin Column-Based Method. PLoS ONE (2015)10(8): e0136133. doi:10.1371/journal.pone.0136133
Zhou W, Fong M Y, Min Y, et al. Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote Metastasis[J]. Cancer cell. 2014, 25(4): 501-515.
Takahashi KJ, Yan IK, Wood J, et al. Involvement of Extracellular Vesicle Long Noncoding RNA (linc-VLDLR) in Tumor Cell Responses to Chemotherapy. Mol Cancer Res.2014 ,12(10): 1377–87.
Li Y, Zheng QP, Bao CY, et al. Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis. Cell Res. 2015, 25(8):981-4.
Melo SA, Sugimoto H, O'Connell JT, et al. Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis. Cancer Cell, 2014.