QUANTITY: 50µL DESCRIPTION: CD45 is a family of single chain transmembraneous glycoproteins consisting of at least four isoformswhich share a common large intracellular domain. Their extracellular domains are heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1. CD45 is expressed on cells of the human hematopoietic lineage (including hematopoietic stem cells) with the exception of mature red cells. It is not detected on differentiated cells of other tissues. It is likely that CD45 plays an important role in signal transduction, inhibition or upregulation of various immunological functions. Antibodies recognising a common epitope on all of the isoforms are termed CD45. SPECIFICITY: Human
ISOTYPE: IgG1
MOLECULAR WEIGHT: ~147KD
TESTED APPLICATIONS: WB,Immunochemistry
APPLICATIONS: WB: 1:2000, IHC: 1:200
*NOTE: Optimal working dilutions must be determined by the end user STORAGE/HANDING:PBS, pH 7.4, containing 0.02% sodium azide as Preservativeand 50% Glycerol.Store at -20°C. Do not aliquot the antibody.
For research use only; not for use as a diagnostic.
Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container,‘s cap.