Anoxia Rapidly Induces Changes in Expression of a Large and Diverse Set of Genes in Endothelial Cells: A. Antonelli, et al.; Int. J. Mol. Sci.
24, 5157 (2023),
Abstract;
Precise manipulation of circadian clock using MnO2 nanocapsules to amplify photodynamic therapy for osteosarcoma: Y.X. Ge, et al.; Mater. Today Bio
19, 100547 (2023),
Abstract;
The impact of hypoxia and oxidative stress on proteo-metabolomic alterations of 3D cholangiocarcinoma models: P. Phukhum, et al.; Sci. Rep.
13, 3072 (2023),
Abstract;
Dimethyloxalylglycine (DMOG), a Hypoxia Mimetic Agent, Does Not Replicate a Rat Pheochromocytoma (PC12) Cell Biological Response to Reduced Oxygen Culture: R. Chen, et al.; Biomolecules
12, 541 (2022),
Abstract;
Hydrogel microcapsules containing engineered bacteria for sustained production and release of protein drugs: C. Han, et al.; Biomaterials
287, 121619 (2022),
Abstract;
Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma: Q. Xu, et al.; Biomaterials
280, 121287 (2022),
Abstract;
Intracellular glucose starvation affects gingival homeostasis and autophagy: R. Li, et al.; Sci. Rep.
12, 1230 (2022),
Abstract;
Intrinsic radical species scavenging activities of tea polyphenols nanoparticles block pyroptosis in endotoxin-induced sepsis: Y. Chen, et al.; ACS Nano
16, 2429 (2022),
Abstract;
Iodinated cyanine dye-based nanosystem for synergistic phototherapy and hypoxia-activated bioreductive therapy: Y. Dong, et al.; Drug Deliv.
29, 238 (2022),
Abstract;
Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma: R. Wang, et al.; Bioact. Mater.
13, 286 (2022),
Abstract;
Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated nanoscale metal-organic framework: W.L. Pan ,et al.; Biomaterials
283, 121559 (2022),
Abstract;
Mitochondrial glutathione depletion nanoshuttles for oxygen-irrelevant free radicals generation: A cascaded hierarchical targeting and theranostic strategy against hypoxic tumor: B. Liang, et al.; ACS Appl. Mater. Interfaces
14, 13038 (2022),
Abstract;
Multifunctional Nanosnowflakes for T1-T2 Double-Contrast Enhanced MRI and PAI Guided Oxygen Self-Supplementing Effective Anti-Tumor Therapy: Y. Lv, et al.; Int. J. Nanomedicine
17, 4619 (2022),
Abstract;
Physiologic flow-conditioning limits vascular dysfunction in engineered human capillaries: K. Haase, et al.; Biomaterials
280, 121248 (2022),
Abstract;
Platinum prodrug nanoparticles inhibiting tumor recurrence and metastasis by concurrent chemoradiotherapy: W. Jiang, et al.; J. Nanobiotechnology
20, 129 (2022),
Abstract;
Strategy for improving cell-mediated vascularized soft tissue formation in a hydrogen peroxide-triggered chemically-crosslinked hydrogel: S.Y. Wei, et al.; J. Tissue. Eng.
13, 20417314221084096 (2022),
Abstract;
Full Text
A cyclic nano-reactor achieving enhanced photodynamic tumor therapy by reversing multiple resistances: P. Liu, et al.; J. Nanobiotechnology
19, 149 (2021),
Abstract;
Full Text
An albumin-based therapeutic nanosystem for photosensitizer/protein co-delivery to realize synergistic cancer therapy: S.L. Ai, et al.; ACS Appl. Bio. Mater.
4, 4946 (2021),
Abstract;
An injectable hydrogel co-loading with cyanobacteria and upconversion nanoparticles for enhanced photodynamic tumor therapy: X. Zhang, et al.; Colloids Surf. B. Biointerfaces
201, 111640 (2021),
Abstract;
Biomimetic nanoreactor for targeted cancer starvation therapy and cascade amplificated chemotherapy: F. Shao, et al.; Biomaterials
274, 120869 (2021),
Abstract;
Bone-targeted erythrocyte-cancer hybrid membrane-camouflaged nanoparticles for enhancing photothermal and hypoxia-activated chemotherapy of bone invasion by OSCC: H. Chen, et al.; J. Nanobiotechnology
19, 342 (2021),
Abstract;
Full Text
Combination of coumarin and doxorubicin induces drug-resistant acute myeloid leukemia cell death: N.S. Al-Abbas, et al.; Heliyon
7, e06255 (2021),
Abstract;
Full Text
Encapsulating an acid-activatable phthalocyanine–doxorubicin conjugate and the hypoxia-sensitive tirapazamine in polymeric micelles for multimodal cancer therapy: X. Guo, et al.; Biomater. Sci.
9, 4936 (2021),
Abstract;
Exploiting the acquired vulnerability of cisplatin-resistant tumors with a hypoxia-amplifying DNA repair-inhibiting (HYDRI) nanomedicine: J. Chen, et al.; Sci. Adv.
7, 5267 (2021),
Abstract;
Extracellular matrix-induced GM-CSF and hypoxia Promote Immune Control of Mycobacterium tuberculosis in Human In Vitro Granulomas: A. Arbues, et al.; Front. Immunol.
12, 727508 (2021),
Abstract;
Full Text
Immune/Hypoxic Tumor Microenvironment Regulation-Enhanced Photodynamic Treatment Realized by pH-Responsive Phase Transition-Targeting Nanobubbles: M. Zhao, et al.; ACS Appl. Mater. Interfaces
13, 32763 (2021),
Abstract;
Mitochondria-targeted and ultrasound-responsive nanoparticles for oxygen and nitric oxide codelivery to reverse immunosuppression and enhance sonodynamic therapy for immune activation: C. Ji, et al.; Theranostics
11, 8587 (2021),
Abstract;
Full Text
MnO2-based nanomotors with active fenton-like Mn2+ delivery for enhanced chemodynamic therapy: J. Ou, et al.; ACS Appl. Mater. Interfaces
13, 38050 (2021),
Abstract;
Mucin 1 regulates the hypoxia response in head and neck cancer cells: K. Utispan, et al.; J. Pharmacol. Sci.
147, 331 (2021),
Abstract;
Ruthenium (II) complexes coordinated to graphitic carbon nitride: Oxygen self-sufficient photosensitizers which produce multiple ROS for photodynamic therapy in hypoxia: F. Wei, et al.; Biomaterials
276, 121064 (2021),
Abstract;
Stratified 3D microtumors as organotypic testing platforms for screening pancreatic cancer therapies: M.V. Monteiro, et al.; Small Methods
5, e2001207 (2021),
Abstract;
Synergy of hypoxia relief and heat shock protein inhibition for phototherapy enhancement: G. Zhang, et al.; J. Nanobiotechnology
19, 9 (2021),
Abstract;
Full Text
The New Serum-Free OptiPASS ® Medium in Cold and Oxygen-Free Conditions: An Innovative Conservation Method for the Preservation of MDA-MB-231 Triple Negative Breast Cancer Spheroids: A. Goisnard, et al.; Cancers
13, 1945 (2021),
Abstract;
Full Text
Biomimetic decoy inhibits tumor growth and lung metastasis by reversing the drawbacks of sonodynamic therapy: H. Zhao, et al.; Adv. Healthc. Mater.
9, e1901335 (2020),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Remodeling extracellular matrix based on functional covalent organic framework to enhance tumor photodynamic therapy: S.B. Wang, et al.; Biomaterials
234, 119772 (2020),
Application(s): Fluorescence microscopy using CT26 cells,
Abstract;
A two-photon excited O2-evolving nanocomposite for efficient photodynamic therapy against hypoxic tumor: R.Q. Li, et al.; Biomaterials
194, 84 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Combinational phototherapy and hypoxia-activated chemotherapy favoring antitumor immune responses: B. Ma, et al.; Int. J. Nanomedicine
14, 4541 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Full Text
Di-(2-ethylhexyl) phthalate (DEHP) inhibits steroidogenesis and induces mitochondria-ROS mediated apoptosis in rat ovarian granulosa cells: A. Tripathi, et al.; Toxicol. Res. (Camb.)
8, 381 (2019),
Application(s): Flow cytometry using granulosa cells,
Abstract;
Encircling granulosa cells protects against di-(2-ethylhexyl)phthalate-induced apoptosis in rat oocytes cultured in vitro: A. Tripathi, et al.; Zygote
27, 203 (2019),
Abstract;
Endogenous oxygen generating multifunctional theranostic nanoplatform for enhanced photodynamic-photothermal therapy and multimodal imaging: K. Wu, et al.; Theranostics
9, 7697 (2019),
Application(s): Confocal microscopy using HeLa cells,
Abstract;
Full Text
Glutathione depletion and dual-model oxygen balance disruption for photodynamic therapy enhancement: W. Li, et al.; Colloids Surf. B Biointerfaces
183, 110453 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Investigation of PPIX-Lipo-MnO2 to enhance photodynamic therapy by improving tumor hypoxia: L. Chudal, et al.; Mater. Sci. Eng. C Mater. Biol. Appl.
104, 109979 (2019),
Application(s): Fluorescence microscopy using MCF-7 cells,
Abstract;
Laser-triggered polymeric lipoproteins for precision tumor penetrating theranostics: R. Wang, et al.; Biomaterials
221, 119413 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Monodispersed copper (I)‐based nano metal–organic framework as a biodegradable drug carrier with enhanced photodynamic therapy efficacy: X. Cai, et al.; Adv. Sci.
6, 1900848 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Full Text
Oral ferroportin inhibitor ameliorates ineffective erythropoiesis in a model of β-thalassemia: V. Manolova, et al.; J. Clin. Invest.
130, 491 (2019),
Application(s): Flow cytometry analysis using mouse red blood cells,
Abstract;
Oxygen-supplementing mesoporous polydopamine nanosponges with WS2 QDs-embedded for CT/MSOT/MR imaging and thermoradiotherapy of hypoxic cancer: Y. Wang, et al.; Biomaterials
220, 119405 (2019),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Self-generating oxygen enhanced mitochondrion-targeted photodynamic therapy for tumor treatment with hypoxia scavenging: Z. Yang, et al.; Theranostics
9, 6809 (2019),
Application(s): Fluorescence microscopy using MKN-45P cells,
Abstract;
Full Text
Solid matrix-supported supercritical CO2 enhances extraction of γ-linolenic acid from the cyanobacterium Arthrospira (Spirulina) platensis and bioactivity evaluation: X. Yang, et al.; Mar. Drugs
17, 203 (2019),
Application(s): Fluorescence microscopy using Zebrafish larvae,
Abstract;
Full Text
All-in-one theranostic nanoplatform based on hollow MoSx for photothermally-maneuvered oxygen self-enriched photodynamic therapy: J. Wang, et al.; Theranostics
8, 955 (2018),
Application(s): Fluorescence microscopy using 4T1 cells,
Abstract;
Full Text
Fluorinated polymeric micelles to overcome hypoxia and enhance photodynamic cancer therapy: Q. Wang, et al.; Biomater. Sci.
6, 3096 (2018),
Abstract;
High glucose-induced oxidative stress impairs proliferation and migration of human gingival fibroblasts: P. Buranasin, et al.; PLoS One
13, e0201855 (2018),
Abstract;
Full Text
Light-enhanced hypoxia-responsive nanoparticles for deep tumor penetration and combined chemo-photodynamic therapy: Z. Li, et al.; Chem. Commun.
54, 13127 (2018),
Abstract;
LSD1 mediated changes in the local redox environment during the DNA damage response: M.L. Duquette, et al.; PLoS One
13, e0201907 (2018),
Abstract;
Full Text
Platelet-mimicking nanoparticles co-loaded with W18O49 and metformin alleviate tumor hypoxia for enhanced photodynamic therapy and photothermal therapy: H. Zuo, et al.; Acta Biomater.
80, 296 (2018),
Abstract;
Tumor starvation induced spatiotemporal control over chemotherapy for synergistic therapy: M.K. Zhang, et al.; Small
14, e1803602 (2018),
Abstract;
Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing: A.C. Chlebowski, et al.; Toxicol. Rep.
4, 202 (2017),
Application(s): Use of hypoxia detection reagent with zebrafish embryos,
Modulation of alveolar macrophage innate response in proinflammatory-, pro-oxidant-, and infection- models by mint extract and chemical constituents: Role of MAPKs: N. Yadav & H. Chandra; Immunobiology
223, 49 (2017),
Abstract;
Nitroimidazole derivatives of polypyridyl ruthenium complexes: Towards understanding their anticancer activity and mode of action: O. Mazuryk, et al.; Eur. J. Pharm. Sci.
101, 43 (2017),
Application(s): Flow cytometry analysis using HaCaT and PANC-1 cells,
Abstract;
Prodrug-embedded angiogenic vessel-targeting nanoparticle: A positive feedback amplifier in hypoxia-induced chemo-photo therapy: D. Guo, et al.; Biomaterials
144, 188 (2017),
Application(s):Condocal Microscopy,
Abstract;
Full Text
Tumor-penetrating nanoparticles for enhanced anticancer activity of combined photodynamic and hypoxia-activated therapy: Y. Wang, et al.; ACS Nano
11, 2227 (2017),
Application(s): Flow cytometry analysis of mouse breast carcinoma cells,
Abstract;
Full Text
Analysis of a nitroreductase-based hypoxia sensor in primary neuronal cultures: B.N. Lizama-Manibusan, et al.; ACS Chem. Neurosci.
7, 1188 (2016),
Abstract;
ERK2 and CHOP restrict the expression of the growth-arrest specific p20K lipocalin gene to G0: M.J. Erb, et al.; Mol. Cell. Biol.
36, 2890 (2016),
Application(s): Hypoxia levels in chick embryo fibroblasts (CEF),
Abstract;
Phagocyte respiratory burst activates macrophage erythropoietin signalling to promote acute inflammation resolution: B. Luo, et al.; Nat. Commun.
7, 12177 (2016),
Application(s): Flow cytometry analysis of hypoxia in exudate leukocytes and peritoneum,
Abstract;
Full Text
Selective advantage of trisomic human cells cultured in non-standard conditions: S.D. Rutledge, et al.; Sci. Rep.
6, 22828 (2016),
Application(s): Fluorescence microscopy on human colorectal adenocarcinoma DLD1 cells,
Abstract;
Full Text
Low-level light in combination with metabolic modulators for effective therapy of injured brain: T. Dong, et al.; J. Cereb. Blood Flow Metab.
35, 1435 (2015),
Application(s): Immunofluorescence Assay,
Abstract;
Full Text
Quantitative measurement of redox potential in hypoxic cells using SERS nanosensors: J. Jiang, et al.; Nanoscale
6, 12104 (2014),
Abstract;