产品背景:
Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.
产品描述:
Human CNTF R alpha, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 36.9 kDa. The predicted N-terminus is Gln 23. The reducing (R) protein migrates as 45-48 kDa in SDS-PAGE due to glycosylation.