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- 详细信息
- 技术资料
- 保存条件：
-20℃
- 克隆性：
单克隆
- 抗体名：
anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
- 规格：
0.1ml/0.2ml
anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体抗原
anthrax Toxin Receptor 1 (ANTXR1)
别名 ANTXR1, ATR, TEM8, 2310008J16Rik, 2810405N18Rik, Antrx1, Tem8
抗原表位
其他选择 pTyr425
适用
其他选择 人
宿主
其他选择 兔
克隆类型 (克隆位点)
多克隆 (RB16635)
标记
其他选择 非结合性
应用范围
其他选择 Dot Blot (DB)
Pubmed 3个引用可参考
规格 400 μL
发货至 中国 (更改)
发货时间 9至13个工作日
产品编号 yb389986
产品细节 anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
免疫原 This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
克隆位点 RB16635
亚型 Ig
特异性 This Phospho-ANTXR1-pY425 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 411~440 amino acids surrounding Y425 of human ANTXR1.
预测反应 Mouse (Murine),Rat (Rattus)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
目标详细情况anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
别名 ANTXR1
背景 ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Synonyms: Anthrax toxin receptor 1, Tumor endothelial marker 8, ANTXR1, ATR, TEM8
分子量 62789 DA
基因ID 84168
UniProt Q9H6X2
研究领域 Cell Structure, Cancer, Phospho-specific antibodies
使用细节anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
应用备注 DB = 1:500
限制 仅限研究用
贮存及处理 anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months
anthrax Toxin Receptor 1 (ANTXR1)
别名 ANTXR1, ATR, TEM8, 2310008J16Rik, 2810405N18Rik, Antrx1, Tem8
抗原表位
其他选择 pTyr425
适用
其他选择 人
宿主
其他选择 兔
克隆类型 (克隆位点)
多克隆 (RB16635)
标记
其他选择 非结合性
应用范围
其他选择 Dot Blot (DB)
Pubmed 3个引用可参考
规格 400 μL
发货至 中国 (更改)
发货时间 9至13个工作日
产品编号 yb389986
产品细节 anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
免疫原 This ANTXR1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.
克隆位点 RB16635
亚型 Ig
特异性 This Phospho-ANTXR1-pY425 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 411~440 amino acids surrounding Y425 of human ANTXR1.
预测反应 Mouse (Murine),Rat (Rattus)
纯化方法 This antibody is purified through a protein A column, followed by peptide affinity purification.
目标详细情况anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
别名 ANTXR1
背景 ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.
Synonyms: Anthrax toxin receptor 1, Tumor endothelial marker 8, ANTXR1, ATR, TEM8
分子量 62789 DA
基因ID 84168
UniProt Q9H6X2
研究领域 Cell Structure, Cancer, Phospho-specific antibodies
使用细节anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
应用备注 DB = 1:500
限制 仅限研究用
贮存及处理 anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
状态 Liquid
浓度 0.5 mg/mL
缓冲液 PBS with 0.09 % (W/V) sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
有效期 6 months
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anthrax Toxin Receptor 1 (ANTXR1) (pTyr425) 抗体
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