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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
GABA B Receptor 1 Antibody抗体
- 抗体英文名:
GABA B Receptor 1 Antibody
- 靶点:
GABA B Receptor 1
- 浓度:
1 mg/ml
- 应用范围:
ICC, IF, WB
- 宿主:
Mouse
- 适应物种:
Human, Mouse, Rat
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb67491
- 级别:
科研级
- 库存:
88
- 供应商:
biorbyt
- 标记物:
Unconjugated
- 克隆性:
Monoclonal
- 亚型:
IgG1
- 免疫原:
Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1
- 规格:
100 ug
别名:GABA-B receptor 1, GABA-B-R1, GABR1_HUMAN, Gamma aminobutyric acid receptor 1, GB1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, GABBR1
免疫原:Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1
克隆性:N93A/49 (Formerly sold as S93A-49)
分子量:115kDa
应用稀释比例:WB (1:1000)
应用注释:1 µg/ml of SMC-403 was sufficient for detection of GABA(B)R1 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
防腐剂:PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated
纯化:Protein G Purified
保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NCBI:NP_112290.2
Entrez:81657
UniProt ID:Q9Z0U4
Note:For research use only.


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文献和实验Characterization of GABA Receptors
'Hara, B.F., Kasch, L.M., Montrose‐Rafizadeh, C., Donovan, D.M., Shimada, S., Antonarakis, S.E., Guggino, W.B., Uhl, G.R., and Kazazian, H.H. 1991. Cloning of the γ‐aminobutyric acid (GABA) ρ 1 cDNA: A GABA receptor subunit highly expressed in the retina
Upregulating G Protein-Coupled Receptors with Receptor Antagonists
The phenomenon of antagonist-induced receptor upregulation is common to many G protein-coupled receptors (GPCRs) such as adrenergic, muscarinic, opioid, cannabinoid, histamine, GABA(B), serotonin, and dopamine receptors
体,进而至轴突,从距约 500微米处发生传导性峰形放电,放电既向细胞体传导,又向中枢(双侧性)传导。大细胞而轴突粗者放电适应快,细轴突的适应慢。具有这样两种性质不同的感受细胞是感受器中最简单的形式。抑制性纤维与树突形成突触联系,其递质被认为是γ -氨基丁酸( GABA)。脊椎动物骨骼肌的牵张感受器为肌梭和腱梭,在肌梭内的梭内纤维有向中性环螺旋形末梢和分散形末梢。这些神经纤维的直径也不同,分属Ⅰ a ,Ⅱ群。在肌梭,无抑制性支配,由远心性γ纤维调节梭内纤维的张力来进行控制。腱梭在腱部,神经纤维属Ⅰ b 群
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