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GABA B Receptor 1 Antibody抗体,o

rb67491,biorbyt
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  • ¥7670
  • biorbyt已认证
  • orb67491
  • 英国
  • 2025年12月04日
  • ICC, IF, WB
  • Mouse
  • Human, Mouse, Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      GABA B Receptor 1 Antibody抗体

    • 抗体英文名

      GABA B Receptor 1 Antibody

    • 靶点

      GABA B Receptor 1

    • 浓度

      1 mg/ml

    • 应用范围

      ICC, IF, WB

    • 宿主

      Mouse

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb67491

    • 级别

      科研级

    • 库存

      88

    • 供应商

      biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal

    • 亚型

      IgG1

    • 免疫原

      Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1

    • 规格

      100 ug

    产品描述:Mouse Anti-Rat GABAB Receptor 1 Monoclonal IgG1

    别名:GABA-B receptor 1, GABA-B-R1, GABR1_HUMAN, Gamma aminobutyric acid receptor 1, GB1, GPRC3A, Gamma-aminobutyric acid type B receptor subunit 1, GABBR1

    免疫原:Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1

    克隆性:N93A/49 (Formerly sold as S93A-49)

    分子量:115kDa

    应用稀释比例:WB (1:1000)

    应用注释:1 µg/ml of SMC-403 was sufficient for detection of GABA(B)R1 in 20 µg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    防腐剂:PBS pH 7.4, 50% glycerol, 0.09% sodium azide *Storage buffer changes when conjugated

    纯化:Protein G Purified

    保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    NCBI:NP_112290.2

    Entrez:81657

    UniProt ID:Q9Z0U4

    Note:For research use only.

    产品细节图片1
    Immunocytochemistry/Immunofluorescence analysis using Mouse Anti-GABA-B Receptor 1 Monoclonal Antibody, Clone N93A/49. Tissue: Neuroblastoma cells (SH-SY5Y). Species: Human. Fixation: 4% PFA for 15 min. Primary Antibody: Mouse Anti-GABA-B Receptor 1 Monoclonal Antibody at 1:50 for overnight at 4°C with slow rocking. Secondary Antibody: AlexaFluor 488 at 1:1000 for 1 hour at RT. Counterstain: Phalloidin-iFluor 647 (red) F-Actin stain; Hoechst (blue) nuclear stain at 1:800, 1.6mM for 20 min at RT. (A) Hoechst (blue) nuclear stain. (B) Phalloidin-iFluor 647 (red) F-Actin stain. (C) GABA-B Receptor 1 Antibody (D) Composite.

    产品细节图片2
    Western Blot analysis of Rat brain membrane lysate showing detection of GABA B Receptor 1 protein using Mouse Anti-GABA B Receptor 1 Monoclonal Antibody, Clone N93A/49. Primary Antibody: Mouse Anti-GABA B Receptor 1 Monoclonal Antibody at 1:1000.

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    图标文献和实验
    相关实验
    • Characterization of GABA Receptors

      'Hara, B.F., Kasch, L.M., Montrose‐Rafizadeh, C., Donovan, D.M., Shimada, S., Antonarakis, S.E., Guggino, W.B., Uhl, G.R., and Kazazian, H.H. 1991. Cloning of the γ‐aminobutyric acid (GABA) ρ 1 cDNA: A GABA receptor subunit highly expressed in the retina

    • Upregulating G Protein-Coupled Receptors with Receptor Antagonists

      The phenomenon of antagonist-induced receptor upregulation is common to many G protein-coupled receptors (GPCRs) such as adrenergic, muscarinic, opioid, cannabinoid, histamine, GABA(B), serotonin, and dopamine receptors

    • 牵张感受器 stretch receptor

      体,进而至轴突,从距约 500微米处发生传导性峰形放电,放电既向细胞体传导,又向中枢(双侧性)传导。大细胞而轴突粗者放电适应快,细轴突的适应慢。具有这样两种性质不同的感受细胞是感受器中最简单的形式。抑制性纤维与树突形成突触联系,其递质被认为是γ -氨基丁酸( GABA)。脊椎动物骨骼肌的牵张感受器为肌梭和腱梭,在肌梭内的梭内纤维有向中性环螺旋形末梢和分散形末梢。这些神经纤维的直径也不同,分属Ⅰ a ,Ⅱ群。在肌梭,无抑制性支配,由远心性γ纤维调节梭内纤维的张力来进行控制。腱梭在腱部,神经纤维属Ⅰ b

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