- ￥3000 - 3999
- Abbiotec
- 美国
- 253670
- 2025年07月16日
- E, WB, IF
- Rabbit
- H, M, R
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- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human PEN2.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M, R
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within human PEN2.
- 目录编号：
253670
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, IF
- 浓度：
见详细说明信息
- 靶点：
PEN2
- 抗体英文名：
PEN2 Antibody
- 抗体名：
PEN2 Antibody
- 规格：
0.1 mg
PEN2 Antibody产品详细介绍：
| 产品名称： | PEN2 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253670 |
| 规格： | 0.1 mg |
| 产品描述： | PEN2, in addition to presenilin, nicastrin, and APH-1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer’s disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either the non-toxic p3 (from the alpha and gamma cleavage site) or the toxic Abeta amyloid peptide (from the beta and gamma cleavage site). It is thought that accumulation of the Abeta peptide is the precursor to Alzheimer’s disease. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human PEN2. |
| 适用物种： | H, M, R |
| 应用范围： | E, WB, IF |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; IF: 1:100-1:500 |
| 别名： | PEN2 ; Presenilin enhancer protein 2; Gamma-secretase subunit PEN-2 |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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PEN2 Antibody_PEN2抗体
￥3000 - 3999
