FcRn, His, Cynomolgus/Rhesus macaque产品图
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FcRn, His, Cynomolgus/Rhesus m

acaque
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  • 询价
  • GenScript/金斯瑞
  • 中国
  • Z04951-100
  • 2026年08月19日
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    • 库存:

      42

    • 供应商:

      广州市左克生物

    • 规格:

      100 μg

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    产品简介:

    货号:Z04951-100

    产品名称:FcRn, His, Cynomolgus/Rhesus macaque

    产品规格:100 μg

    产品介绍文本:The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT&B2M h...

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    产品简介HTML:

    产品简介
    Species Cynomolgus/Rhesus macaque
    Protein Construction
    FcRn [Ala24-Ser297 (FCGRT) and Ile21-Met119 (B2M)]
    Accession # Q8SPV9 (FCGRT) & Q8SPW0 (B2M)
    His
    N-term C-term
    Purity > 95% as determined by BisTris PAGE
    Endotoxin Level Less than 1EU per μg by the LAL method.
    Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
    Expression System HEK293
    Theoretical Molecular Weight 31.5 kDa (FCGRT) and 11.6 kDa (B2M)
    Apparent Molecular Weight Due to glycosylation, the protein migrates to 35-38 kDa (FCGRT) and 13-15 kDa (B2M) based on Bis-Tris PAGE result.
    Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
    Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
    Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

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    技术背景HTML:

    技术背景
    Target Background The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT&B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
    Synonyms FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M

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