IL-22 (C-hIgG2 Fc), Human, Rec

IL-22 (C-hIgG2 Fc), Human, RecombinantIL-22 (C-hIgG2 Fc), Human, RecombinantInterleukin-22;IL-22;Cytokine Zcyto18;IL-10-related T-cell-Derived-inducible factor;IL-TIF;IL22

IL-22 (C-hIgG2 Fc), Human, Recombinant PCK185

背景介绍：Interleukin-22 (IL-22) is a member of a group of the IL-10 family, a class of potent mediators of cellular inflammatory responses. IL-22 is produced by activated DC and T cells. IL-22 and IL-10 Receptor chains play a role in cellular targeting and signal transduction. It can initiate and regulate innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 along with IL-17 likely plays a role in the coordinated response of both adaptive and innate immune systems. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10. Biological activity of IL-22 is initiated by binding to a cell-surface complex consisting of IL-22R1 and IL-10R2 Receptor chains. IL-22 biological activity is further regulated by interactions with a soluble binding Protein, IL-22BP. IL-22BP and an extracellular region of IL-22R1 share sequence similarity. In some cases, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by Cytokine IL-17A.

产品形态	粉末
产品规格	1mg、10μg、50μg、500μg
别名	Interleukin-22;IL-22;Cytokine Zcyto18;IL-10-related T-cell-Derived-inducible factor;IL-TIF;IL22
物种	人
表达宿主	Human Cells
序列信息	Ala34-Ile179
检索号	Q9GZX6
分子量	43.4 kDa
表观分子量	50-62 kDa
标签	C-hIgG2 Fc
纯度	> 95% as determined by reducing SDS-PAGE.
内毒素	< 0.1 EU/μg
储存条件	Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输条件	Ambient temperature or ice pack.
有效期	12个月
制剂	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in sterile water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
体系描述	GMP生产和质量体系 公司符合cGMP的要求，已通过NMPA的第一类医疗器械生产备案，且通过ISO 13485和ISO 9001标准认证。公司生产的IL-22 (C-hIgG2 Fc), Human, Recombinant符合ISO 9001的cGMP标准。

产品问答FAQs：

Q：细胞因子离心前需要放置室温吗？

A：不用提前放置室温.

Q：细胞因子加无菌水溶解后需要再次离心吗？

A：加了无菌水后，如果没有挂壁现象是不用离心的，如果您放置了一段时间，再次使用时是可以使用离心机离心的

Q：细胞因子用无菌水配成了100ug/mL母液，用于实验时，需要的终浓度为10ng/mL，可以用培养基直接稀释？还是需要通过PBS（含5%海藻糖）进一步稀释才行呢？

A：如果是直接做实验，可以直接添加培养基进行稀释配置。 如果是需要长时间保存的话，需要使用含载体蛋白(如0.1%BSA，10% FBS，5%HSA或5%海藻糖)的溶液进一步释后分装保存于-5~-20℃或者-80℃冰箱

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IL-22 (C-hIgG2 Fc), Human, Recombinant Ambient temperature or ice pack. Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. 12个月