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- 文献和实验
- 技术资料
- 库存:
999
- 保质期:
12个月
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 保存条件:
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- 规格:
100 μg/20 μg
| 规格: | 100 μg | 产品价格: | ¥3600.00 |
|---|---|---|---|
| 规格: | 20 μg | 产品价格: | ¥1200.00 |
产品简称:ApoH
英文名称:Recombinant Human ApoH Protein (His Tag)

背景:Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. It is an essential cofactor for the binding of certain antiphospholipid antibodies (APA) to anionic phospholipid. APOH binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. APOH may prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. The activity of APOH appears to involve the binding of agglutenating, negatively charged compounds, and inhibits agglutenation by the contact activation of the intrinsic blood coagulation pathway. APOH causes a reduction of the prothrombinase binding sites on platelets and reduces the activation caused by collagen when thrombin is present at physiological serum concentrations of APOH suggesting a regulatory role of APOH in coagulation. APOH plasma concentrations are strongly associated to metabolic syndrome alterations and vascular disease in type 2 diabetic and could be considered as a clinical marker of cardiovascular risk. APOH is found on several classes of lipoproteins, and is involved in the activation of lipoprotein lipase in lipid metabolism. This single-chain glycoprotein also has been implicated in several physiologic pathways including coagulation and the production of hypertension, which are related to the pathogenesis of primary cerebral hemorrhage (PICH).
运输条件:This product is provided as lyophilized powder which is shipped with ice packs.
实验图:


Elabscience供应Recombinant Human ApoH protein (His Tag),这些蛋白质中的大多数纯度≥95%,内毒素水平≤1.0EU/μg,并且已经过活性验证,助力您科学实验。
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