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- 文献和实验
- 技术资料
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 规格:
10 μg/50 μg
| 规格: | 10 μg | 产品价格: | ¥1036.00 |
|---|---|---|---|
| 规格: | 50 μg | 产品价格: | ¥2506.00 |
产品简称:SCF
英文名称:Recombinant Mouse SCF/c-Kit Ligand Protein

背景:Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5.
运输条件:This product is provided as lyophilized powder which is shipped with ice packs.
实验图:


Elabscience供应Recombinant Mouse SCF/c-Kit Ligand Protein,这些蛋白质中的大多数纯度≥95%,内毒素水平≤1.0EU/μg,并且已经过活性验证,助力您科学实验。
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文献和实验The CRE Luc Mouse Model for Bioimaging Ligand Activation of G Protein-Coupled Receptors
from a luciferase reporter have been used extensively in vitro with high-throughput screens (HTS) of large chemical compound libraries. We have generated a transgenic mouse model (CRE luc) with a luciferase reporter under the control of a synthetic promoter
The Use of Recombinant Fusion Proteases in the Affinity Purification of Recombinant Proteins
of interest, but some affinity tails are able to be linked to either the N- or C-terminus of the protein of interest. The choice of affinity tail to use for the expression of any particular protein is empirical since the factors leading to the high expression of recombinant
Ligand Characterization Using Microphysiometry
the use of a Cytosensor microphysiometer for functional characterization of an agonist and antagonist to a G protein?coupled receptor, the muscarinic M1 receptor. Concentration?response profiles are used to calculate values for the EC50 of the response
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